Peptide Information

General Information of This Peptide
Peptide ID
BTDP002665
Peptide Name
Mambaquaretin-4
Symonym
Upsilon-Dv2c
Species
Dendroaspis viridis (Western green mamba)
Uniprot Name
MAMB4_DENVI
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
RPSFCNLPVKPGPCNGFFSAFYYSQKTNKCHSFTYGGCKGNANRFSTIEKCRRTCVC
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Mutant Sequence
RPSFCNLPVKPGPCSGFFSAFYYSQKTNKCHSFTYGGCRGNGNRFRTIEECRRTCVG
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Sequence Length
57
Mass(Da)
6434
Sequence Removed Signal Peptide
RPSFCNLPVKPGPCSGFFSAFYYSQKTNKCHSFTYGGCRGNGNRFRTIEECRRTCVG
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Disulfide Bond
5-55;14-38;30-51
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Dendroaspis
Species: Dendroaspis viridis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    V2R Inhibition constant
7.34 nM
 . . [1]
References
Ref 1 A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor. Br J Pharmacol. 2022 Jul;179(13):3470-3481. doi: 10.1111/bph.15814. Epub 2022 Feb 28.
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