General Information of This Peptide
Peptide ID
BTDP002562
Peptide Name
Mambalgin-3
Symonym
Mamb-3
Species
Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps)
Uniprot Name
3SX3_DENAN
Alphafold ID
C0HJB0
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: C0HJB0
Sequence
LKCYQHGKVVTCHRDMKFCYHNIGMPFRNLKLILQGCSSSCSETENNKCCSTDRCNK
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Sequence Length
57
Mass (Da)
6575
Sequence Removed Signal Peptide
LKCYQHGKVVTCHRDMKFCYHNIGMPFRNLKLILQGCSSSCSETENNKCCSTDRCNK
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Disulfide Bond
3-19;12-37;41-49;50-55
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Dendroaspis
Species: Dendroaspis angusticeps
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    acid-sensing ion channel (ASIC) IC50
17 nM
. . [1]
 Target Info    acid-sensing ion channel (ASIC) IC50
44 nM
. . [1]
 Target Info    ASIC1a-ASIC2b IC50
252 nM
. . [1]
References
Ref 1 Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels. Toxicon. 2013 Dec 1;75:187-204. doi: 10.1016/j.toxicon.2013.04.008. Epub 2013 Apr 26.
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