Peptide Information

General Information of This Peptide
Peptide ID
BTDP001584
Peptide Name
Secapin
Symonym
AcSecapin-1
Species
Apis cerana (Indian honeybee)
Uniprot Name
SECP_APICE
Alphafold ID
A0A0K1YW63
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: A0A0K1YW63
Sequence
MRFQVYILHLCFFILVVLTYLSQGQSYTTTTTTSTTEQPTFLQKIHETFKKVKENAKIHN
LYIFDPPTWIYTTTTEKPVESTENFDITNRQLITVPVRCPPNYDFIKGRCREKIP
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Sequence Length
115
Mass (Da)
13570
Signal Sequence
MRFQVYILHLCFFILVVLTYLSQG
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Sequence Removed Signal Peptide
QSYTTTTTTSTTEQPTFLQKIHETFKKVKENAKIHNLYIFDPPTWIYTTTTEKPVESTEN
FDITNRQLITVPVRCPPNYDFIKGRCREKIP
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Disulfide Bond
99-110
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Insecta
Order: Hymenoptera
Family: Apidae
Genus: Apis
Species: Apis cerana
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    porcine elastase Inhibition constant
125.62 nM
 . . [1]
 Target Info    trypsin Inhibition constant
127.25 nM
 . . [1]
 Target Info    proteinase K Inhibition constant
271.76 nM
 . . [1]
 Target Info    chymotrypsin Inhibition constant
432.59 nM
 . . [1]
 Target Info    elastase Inhibition constant
469.9 nM
 . . [1]
 Target Info    microbial serine proteases subtilisin A Inhibition constant
492.77 nM
 . . [1]
 Target Info    plasmin Inhibition constant
502.91 nM
 . . [1]
 Target Info    trypsin IC50
80.02 nM
 . . [1]
 Target Info    porcine elastase IC50
94.7 nM
 . . [1]
 Target Info    proteinase K IC50
189.43 nM
 . . [1]
 Target Info    elastase IC50
347.81 nM
 . . [1]
 Target Info    microbial serine proteases subtilisin A IC50
379.2 nM
 . . [1]
 Target Info    chymotrypsin IC50
393.78 nM
 . . [1]
 Target Info    plasmin IC50
457.98 nM
 . . [1]
References
Ref 1 Secapin, a bee venom peptide, exhibits anti-fibrinolytic, anti-elastolytic, and anti-microbial activities. Dev Comp Immunol. 2016 Oct;63:27-35. doi: 10.1016/j.dci.2016.05.011. Epub 2016 May 18.
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