Peptide Information

General Information of This Peptide
Peptide ID
BTDP001224
Peptide Name
rHwTx-IV (Y33T)
3D Structure
Download
2D Sequence
3D Structure
Source
Predict by Alphafold2
?
Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
ECLEIFKACNPSNDQCCKSSKLVCSRKTRWCKYQIGK
   Click to Show/Hide
Mutant Sequence
ECLEIFKACNPSNDQCCKSSKLVCSRKTRWCKTQIGK
   Click to Show/Hide
Sequence Length
37
Mass(Da)
4237
Sequence Removed Signal Peptide
ECLEIFKACNPSNDQCCKSSKLVCSRKTRWCKTQIGK
   Click to Show/Hide
Disulfide Bond
2-17;9-24;16-31
        Click to Show/Hide the Complete Species Lineage
N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.2 pIC50
6.2 ± 0.05 .
 . . [1]
 Target Info    Nav1.7 pIC50
7.2 ± 0.07 .
 . . [1]
References
Ref 1 Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa(v)1.7. J Biol Chem. 2020 Jan 31;295(5):1315-1327. doi: 10.1074/jbc.RA119.011318. Epub 2019 Dec 23.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.