Peptide Information

General Information of This Peptide
Peptide ID
BTDP001159
Peptide Name
PTx2-3067
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
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Mutant Sequence
QCQKWMQTCDSARKCCEGFRCRLWCRKELL
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Sequence Length
30
Mass(Da)
3710
Sequence Removed Signal Peptide
QCQKWMQTCDSARKCCEGFRCRLWCRKELL
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Disulfide Bond
2-16;9-21;15-25
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
48.3 nM
 . . [1]
References
Ref 1 Computational design of peptides to target Na(V)1.7 channel with high potency and selectivity for the treatment of pain. Elife. 2022 Dec 28;11:e81727. doi: 10.7554/eLife.81727.
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