Peptide Information

General Information of This Peptide
Peptide ID
BTDP000957
Peptide Name
AgTx2 (K27M)
Symonym
AgTx2 (K27M)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
GVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPK
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Mutant Sequence
GVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPKGSGGSGGSGGTGGAGGATSTMV
SKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLV
TTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVN
RIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADH
YQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGITLGMDELYK
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Sequence Length
297
Mass(Da)
32436
Sequence Removed Signal Peptide
GVPINVSCTGSPQCIKPCKDAGMRFGKCMNRKCHCTPKGSGGSGGSGGTGGAGGATSTMV
SKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLV
TTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVN
RIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADH
YQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGITLGMDELYK
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.6 IC50
1.3 nM
 .
Blocker
 [1]
References
Ref 1 AgTx2-GFP, Fluorescent Blocker Targeting Pharmacologically Important K(v)1.x (x = 1, 3, 6) Channels. Toxins (Basel). 2023 Mar 18;15(3):229. doi: 10.3390/toxins15030229.
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