Peptide Information

General Information of This Peptide
Peptide ID
BTDP000911
Peptide Name
KTX-1 (G7L,S8P,P9Q,L12I,R28K,H31R)
Symonym
KTX-1 (G7L,S8P,P9Q,L12I,R28K,H31R)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTP
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Mutant Sequence
INVKCSLPQQCIKPCKDAGMRFGKCMNKKCRCYS
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Sequence Length
34
Mass(Da)
3877
Sequence Removed Signal Peptide
INVKCSLPQQCIKPCKDAGMRFGKCMNKKCRCYS
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 Inhibition rate .
1 μM
Blocker
 [1]
References
Ref 1 A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22211-6. doi: 10.1073/pnas.0910123106. Epub 2009 Dec 10.
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