Peptide Information

General Information of This Peptide
Peptide ID
BTDP000840
Peptide Name
Kcug1 (K11A)
Symonym
Kcug1 (K11A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
QFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
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Mutant Sequence
QFTDVKCTASAQCWPVCNQMFGKPNGKCMNGKCRCYS
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Sequence Length
37
Mass(Da)
4130
Sequence Removed Signal Peptide
QFTDVKCTASAQCWPVCNQMFGKPNGKCMNGKCRCYS
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 Inhibition rate
88.1 %
1 μM
Blocker
 [1]
References
Ref 1 Different pharmacological properties between scorpion toxin BmKcug2 and its degraded analogs highlight the diversity of K(+) channel blockers from thermally processed scorpions. Int J Biol Macromol. 2021 May 1;178:143-153. doi: 10.1016/j.ijbiomac.2021.02.155. Epub 2021 Feb 23.
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