Peptide Information

General Information of This Peptide
Peptide ID
BTDP000839
Peptide Name
ChTx-c (E18Q,K19Y,Y21H,Y36F)
Symonym
ChTx-c (E18Q,K19Y,Y21H,Y36F)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
QFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
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Mutant Sequence
QFTNVSCTTSKECWSVCQYLHNTSRGKCMNKKCRCFS
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Sequence Length
37
Mass(Da)
4287
Sequence Removed Signal Peptide
QFTNVSCTTSKECWSVCQYLHNTSRGKCMNKKCRCFS
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Inhibition constant
0.027 nM
 .
Blocker
 [1]
References
Ref 1 Revealing the molecular determinants of neurotoxin specificity for calcium-activated versus voltage-dependent potassium channels. Biochemistry. 2007 May 8;46(18):5358-64. doi: 10.1021/bi700150t. Epub 2007 Apr 18.
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