Peptide Information

General Information of This Peptide
Peptide ID
BTDP000769
Peptide Name
ChTX
Symonym
ChTX
3D Structure
Download
2D Sequence
3D Structure
Source
Predict by Alphafold2
?
Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
QFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
   Click to Show/Hide
Mutant Sequence
QFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
   Click to Show/Hide
Sequence Length
37
Mass(Da)
4420
Sequence Removed Signal Peptide
QFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS
   Click to Show/Hide
        Click to Show/Hide the Complete Species Lineage
N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa Dissociation constant
0.1 nM
 .
Blocker
 [1]
 Target Info    Kv Dissociation constant
0.29 nM
 .
Blocker
 [2]
 Target Info    KCa Dissociation constant
860 nM
 .
Blocker
 [3]
References
Ref 1 Characterization of high affinity binding sites for charybdotoxin in sarcolemmal membranes from bovine aortic smooth muscle. Evidence for a direct association with the high conductance calcium-activated potassium channel. J Biol Chem. 1989 Dec 15;264(35):20902-9.
Ref 2 Characterization of high affinity binding sites for charybdotoxin in synaptic plasma membranes from rat brain. Evidence for a direct association with an inactivating, voltage-dependent, potassium channel. J Biol Chem. 1990 Sep 15;265(26):15564-71.
Ref 3 Analysis of the blocking activity of charybdotoxin homologs and iodinated derivatives against Ca2+-activated K+ channels. J Membr Biol. 1989 Aug;109(3):269-81. doi: 10.1007/BF01870284.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.