General Information of This Peptide
Peptide ID
BTDP000736
Peptide Name
Kunitz-type serine protease inhibitor HCRG21 (S5L)
Symonym
Kunitz-type serine protease inhibitor HCRG21 (S5L)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
RGICLEPKVVGPCTAYFRRFYFDSETGKCTPFIYGGCEGNGNNFETLRACRAICRA
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Mutant Sequence
RGICLEPKVVGPCTAYFRRFYFDSETGKCTPFIYGGCEGNGNNFETLRACRAICRA
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Sequence Length
56
Mass(Da)
6254
Sequence Removed Signal Peptide
RGICLEPKVVGPCTAYFRRFYFDSETGKCTPFIYGGCEGNGNNFETLRACRAICRA
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1 IC50
15.6 μM
.
Blocker
[1]
References
Ref 1 Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities. Biomedicines. 2020 Nov 4;8(11):473. doi: 10.3390/biomedicines8110473.
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