Peptide Information

General Information of This Peptide
Peptide ID
BTDP000730
Peptide Name
PhlTx1-S8A
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
ACLGQWDSCDPKASKCCPNYACEWKYPWCRYKLF
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Mutant Sequence
ACLGQWDACDPKASKCCPNYACEWKYPWCRYKLF
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Sequence Length
34
Mass(Da)
4049
Sequence Removed Signal Peptide
ACLGQWDACDPKASKCCPNYACEWKYPWCRYKLF
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Disulfide Bond
2-17;9-22;16-29
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
179.5 ± 118.4 nM
 . . [1]
References
Ref 1 Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates. Toxins (Basel). 2019 Aug 22;11(9):484. doi: 10.3390/toxins11090484.
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