Peptide Information

General Information of This Peptide
Peptide ID
BTDP000381
Peptide Name
Kappa-M-RIIIJ (K10R,H11L)
Symonym
Kappa-M-RIIIJ (K10R,H11L)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Mutant Sequence
LPPCCTPPKRLCPAPACKYKPCCKS
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Sequence Length
25
Mass(Da)
2811
Sequence Removed Signal Peptide
LPPCCTPPKRLCPAPACKYKPCCKS
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.2 IC50
48 nM
 .
Blocker
 [1]
References
Ref 1 Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins. J Biol Chem. 2010 May 14;285(20):14882-14889. doi: 10.1074/jbc.M109.068486. Epub 2010 Mar 10.
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