Peptide Information

General Information of This Peptide
Peptide ID
BTDP000317
Peptide Name
JZTX-XI
Species
Chilobrachys guangxiensis (Chinese earth tiger tarantula) (Chilobrachys jingzhao)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
ECRKMFGGCSVDSDCCAHLGCKPTLKYCAWDGTF
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Sequence Length
34
Mass (Da)
3733
Sequence Removed Signal Peptide
ECRKMFGGCSVDSDCCAHLGCKPTLKYCAWDGTF
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Disulfide Bond
2-16;9-21;15-28
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Chilobrachys
Species: Chilobrachys guangxiensis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.5 IC50
0.124 ± 0.026 μM
 . . [1]
References
Ref 1 The tarantula toxin jingzhaotoxin-XI (-theraphotoxin-Cj1a) regulates the activation and inactivation of the voltage-gated sodium channel Nav1.5. Toxicon. 2014 Dec 15;92:6-13. doi: 10.1016/j.toxicon.2014.09.002. Epub 2014 Sep 18.
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