Peptide Information

General Information of This Peptide
Peptide ID
BTDP000261
Peptide Name
HNTX-III (Gly1Lys)
3D Structure
Download
2D Sequence
3D Structure
Source
Predict by Alphafold2
?
Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
GCKGFGDSCTPGKNECCPNYACSSKHKWCKVYL
   Click to Show/Hide
Mutant Sequence
KCKGFGDSCTPGKNECCPNYACSSKHKWCKVYL
   Click to Show/Hide
Sequence Length
33
Mass(Da)
3686
Sequence Removed Signal Peptide
KCKGFGDSCTPGKNECCPNYACSSKHKWCKVYL
   Click to Show/Hide
Disulfide Bond
2-17;9-22;16-29
        Click to Show/Hide the Complete Species Lineage
N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
0.150 ± 0.024 μM
 . . [1]
References
Ref 1 Engineering of highly potent and selective HNTX-III mutant against hNa(v)1.7 sodium channel for treatment of pain. J Biol Chem. 2021 Jan-Jun;296:100326. doi: 10.1016/j.jbc.2021.100326. Epub 2021 Jan 23.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.