Peptide Information

General Information of This Peptide
Peptide ID
BTDP000246
Peptide Name
HNTX-I
Species
Cyriopagopus hainanus (Chinese bird spider) (Haplopelma hainanum)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
ECKGFGKSCVPGKNECCSGYACNSRDKWCKVLL
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Sequence Length
33
Mass (Da)
3614
Sequence Removed Signal Peptide
ECKGFGKSCVPGKNECCSGYACNSRDKWCKVLL
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Disulfide Bond
2-17;9-23;17-30
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Theraphosidae
Genus: Cyriopagopus
Species: Cyriopagopus hainanus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
>10 μM
 . . [1]
References
Ref 1 Engineering Gain-of-Function Analogues of the Spider Venom Peptide HNTX-I, A Potent Blocker of the hNa(V)1.7 Sodium Channel. Toxins (Basel). 2018 Sep 4;10(9):358. doi: 10.3390/toxins10090358.
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