General Information of This Peptide
Peptide ID
BTDP000065
Peptide Name
Ca2a-K18A
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
ACLGFGEKCNPSNDKCCKSSSLVCSQKHKWCKYDL
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Mutant Sequence
ACLGFGEKCNPSNDKCCASSSLVCSQKHKWCKYDL
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Sequence Length
35
Mass(Da)
3854
Sequence Removed Signal Peptide
ACLGFGEKCNPSNDKCCASSSLVCSQKHKWCKYDL
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Disulfide Bond
2-17;9-24;16-31
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Nav1.7 IC50
683.3 ± 130.5 μM
. . [1]
References
Ref 1 General mechanism of spider toxin family I acting on sodium channel Nav1.7. Zool Res. 2022 Sep 18;43(5):886-896. doi: 10.24272/j.issn.2095-8137.2022.185.
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