Peptide Information

General Information of This Peptide
Peptide ID
BTDP008944
Peptide Name
ErgTx1 (Q18A,A35M)
Symonym
Erg Tx1 (Q18A,A35M)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
DRDSCVDKSRCAKYGYYQECQDCCKNAGHNGGTCMFFKCKCT
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Mutant Sequence
DRDSCVDKSRCAKYGYYAECQDCCKNAGHNGGTCMFFKCKCA
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Sequence Length
42
Mass(Da)
4673
Sequence Removed Signal Peptide
DRDSCVDKSRCAKYGYYAECQDCCKNAGHNGGTCMFFKCKCA
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        Click to Show/Hide the Complete Species Lineage
N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv11 Dissociation constant
72.9 nM
 .
Blocker
 [1]
References
Ref 1 Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K(+) channel toxins. Biochem Biophys Res Commun. 2012 Dec 7;429(1-2):111-6. doi: 10.1016/j.bbrc.2012.10.065. Epub 2012 Oct 24.
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