Peptide Information

General Information of This Peptide
Peptide ID
BTDP008897
Peptide Name
Toxin APETx2_A33F_L34A
Symonym
Toxin APETx2 (A33F,L34A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFAGTCCTPAD
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Sequence Length
42
Mass (Da)
4519
Sequence Removed Signal Peptide
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFAGTCCTPAD
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Disulfide Bond
4-30;6-37;20-38
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv11 . . . . [1]
References
Ref 1 Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores. J Med Chem. 2014 Nov 13;57(21):9195-203. doi: 10.1021/jm501400p. Epub 2014 Nov 4.
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