Peptide Information

General Information of This Peptide
Peptide ID
BTDP008801
Peptide Name
ShK (S20A)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
RSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
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Mutant Sequence
RSCIDTIPKSRCTAFQCKHAMKYRLSFCRKTCGTC
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Sequence Length
35
Mass(Da)
4039
Sequence Removed Signal Peptide
RSCIDTIPKSRCTAFQCKHAMKYRLSFCRKTCGTC
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Disulfide Bond
3-28;12-32;17-35
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Dissociation constant
0.32 nM
 .
Blocker
 [1]
References
Ref 1 Structural conservation of the pores of calcium-activated and voltage-gated potassium channels determined by a sea anemone toxin. J Biol Chem. 1999 Jul 30;274(31):21885-92. doi: 10.1074/jbc.274.31.21885.
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