Peptide Information

General Information of This Peptide
Peptide ID
BTDP008780
Peptide Name
ScyTx (M7R)
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Original Sequence
AFCNLRMCQLSCRSLGLLGKCIGDKCECVKH
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Mutant Sequence
AFCNLRRCQLSCRSLGLLGKCIGDKCECVKH
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Sequence Length
31
Mass(Da)
3449
Sequence Removed Signal Peptide
AFCNLRRCQLSCRSLGLLGKCIGDKCECVKH
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Disulfide Bond
3-21;8-26;12-28
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N.A.
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa2 IC50
8 pM
 .
Blocker
 [1]
 Target Info    KCa2 IC50
0.08 nM
 .
Blocker
 [1]
References
Ref 1 Leiurotoxin I, a scorpion toxin specific for Ca(2+)-activated K+ channels. Structure-activity analysis using synthetic analogs. Int J Pept Protein Res. 1994 May;43(5):486-95. doi: 10.1111/j.1399-3011.1994.tb00548.x.
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