Peptide Information

General Information of This Peptide
Peptide ID
BTDP008713
Peptide Name
Potassium channel toxin TcoKIK
Species
Tityus costatus (Brazilian scorpion)
Uniprot Name
KBX2_TITCO
Alphafold ID
Q0GY42
3D Structure
Download
2D Sequence
3D Structure
Source
RSCB PDB: 7LGL
Sequence
KIKSGWERLTSESEYACPAIDKFCEDHCAAKKAVGKCDDFKCNCIKL
   Click to Show/Hide
Sequence Length
47
Mass (Da)
5284
Sequence Removed Signal Peptide
KIKSGWERLTSESEYACPAIDKFCEDHCAAKKAVGKCDDFKCNCIKL
   Click to Show/Hide
Disulfide Bond
17-37;24-42;28-44
PDB ID
7LGL
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus costatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv7.1 Inhibition rate .
100 μM
Blocker
 [3]
References
Ref 1 Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components. Peptides. 2007 Jan;28(1):31-7. doi: 10.1016/j.peptides.2006.06.012. Epub 2006 Dec 1.
Ref 2 The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function. Toxicon. 2005 Mar 1;45(3):273-83. doi: 10.1016/j.toxicon.2004.10.014. Epub 2004 Dec 10.
Ref 3 Beta-KTx14.3, a scorpion toxin, blocks the human potassium channel KCNQ1. Biochim Biophys Acta Proteins Proteom. 2023 Jul 1;1871(4):140906. doi: 10.1016/j.bbapap.2023.140906. Epub 2023 Mar 12.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.