Peptide Information

General Information of This Peptide
Peptide ID
BTDP008667
Peptide Name
Potassium channel toxin alpha-KTx 6.5
Symonym
Pi-7; Toxin-7
Species
Pandinus imperator (Emperor scorpion)
Uniprot Name
KAX65_PANIM
Alphafold ID
P58490
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 1QKY
Sequence
DEAIRCTGTKDCYIPCRYITGCFNSRCINKSCKCYGCT
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Sequence Length
38
Mass (Da)
4291
Sequence Removed Signal Peptide
DEAIRCTGTKDCYIPCRYITGCFNSRCINKSCKCYGCT
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Disulfide Bond
6-27;12-32;16-34;22-37
PDB ID
1QKY
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Scorpionidae
Genus: Pandinus
Species: Pandinus imperator
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Shaker Inhibition rate .
100 nM
Blocker
 [1]
References
Ref 1 Two similar peptides from the venom of the scorpion Pandinus imperator, one highly effective blocker and the other inactive on K+ channels. Toxicon. 1998 May;36(5):759-70. doi: 10.1016/s0041-0101(97)00163-3.
Ref 2 Pi7, an orphan peptide from the scorpion Pandinus imperator: a 1H-NMR analysis using a nano-NMR Probe. Biochemistry. 1999 Dec 21;38(51):16756-65. doi: 10.1021/bi991685m.
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