Peptide Information

General Information of This Peptide
Peptide ID
BTDP008622
Peptide Name
Potassium channel toxin gamma-KTx 1.7
Symonym
CeErgTx4
Species
Centruroides elegans (Bark scorpion)
Uniprot Name
KGX17_CENEL
Alphafold ID
P0C892
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C892
Sequence
DRDSCVDKSRCSKYGYYQECQDCCKKAGHNGGTCMFFKCKCA
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Sequence Length
42
Mass (Da)
4768
Sequence Removed Signal Peptide
DRDSCVDKSRCSKYGYYQECQDCCKKAGHNGGTCMFFKCKCA
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Disulfide Bond
5-23;11-34;20-39;24-41
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides elegans
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv11.3 Dissociation constant
0.88 nM
 .
Blocker
 [1]
 Target Info    Kv11 Dissociation constant
12.8 nM
 .
Blocker
 [1]
 Target Info    Kv11.2 Inhibition rate .
210 nM
Blocker
 [1]
References
Ref 1 Two novel ergtoxins, blockers of K+-channels, purified from the Mexican scorpion Centruroides elegans elegans. Neurochem Res. 2008 Aug;33(8):1525-33. doi: 10.1007/s11064-008-9634-8. Epub 2008 Mar 13.
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