Peptide Information

General Information of This Peptide
Peptide ID
BTDP008613
Peptide Name
Potassium channel toxin alpha-KTx 18.3
Symonym
Toxin TdK3
Species
Tityus discrepans (Venezuelan scorpion)
Uniprot Name
KA183_TITDI
Alphafold ID
P0C1X6
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C1X6
Sequence
MHFSGVAFILISMVLIGSIFETTVEAGEGPKSDCKPDLCEAACKDLGKPMDFCKDGTCKC
KD
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Sequence Length
62
Mass (Da)
6633
Sequence Removed Signal Peptide
GEGPKSDCKPDLCEAACKDLGKPMDFCKDGTCKCKD
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Disulfide Bond
34-53;39-58;43-60
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus discrepans
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2], [3]
References
Ref 1 Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans. Biochimie. 2009 Aug;91(8):1010-9. doi: 10.1016/j.biochi.2009.05.005. Epub 2009 May 24.
Ref 2 Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins. Proteomics. 2006 Jun;6(12):3718-27. doi: 10.1002/pmic.200500525.
Ref 3 Looking over toxin-K(+) channel interactions. Clues from the structural and functional characterization of -KTx toxin Tc32, a Kv1.3 channel blocker. Biochemistry. 2012 Mar 6;51(9):1885-94. doi: 10.1021/bi201713z. Epub 2012 Feb 27.
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