Peptide Information

General Information of This Peptide
Peptide ID
BTDP008599
Peptide Name
Delta-aiptatoxin-Adi1a
Symonym
Ion channel modifier Ade-1
Species
Exaiptasia diaphana (Tropical sea anemone) (Aiptasia pulchella)
Uniprot Name
NAU1A_EXADI
Alphafold ID
E3P6S4
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: E3P6S4
Sequence
MKTAMLIAVLGFCAALCFVESSHEEEREAAVYLTDLVSKAESAIKRGIPCRCDKNSDELN
GEQSYMNGNCGDGWKKCRSVNAIFNCCQRV
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Sequence Length
90
Mass (Da)
9929
Sequence Removed Signal Peptide
GIPCRCDKNSDELNGEQSYMNGNCGDGWKKCRSVNAIFNCCQRV
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Disulfide Bond
50-86;52-77;70-87
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Aiptasiidae
Genus: Exaiptasia
Species: Exaiptasia diaphana
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . . . [1], [2]
References
Ref 1 AdE-1, a new inotropic Na(+) channel toxin from Aiptasia diaphana, is similar to, yet distinct from, known anemone Na(+) channel toxins. Biochem J. 2013 Apr 1;451(1):81-90. doi: 10.1042/BJ20121623.
Ref 2 The sea anemone toxin AdE-1 modifies both sodium and potassium currents of rat cardiomyocytes. Biochem J. 2014 Jul 1;461(1):51-9. doi: 10.1042/BJ20131454.
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