Peptide Information

General Information of This Peptide
Peptide ID
BTDP008594
Peptide Name
Potassium channel toxin gamma-KTx 1.10
Species
Centruroides margaritatus (Central American bark Scorpion)
Uniprot Name
KGX1A_CENMA
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
DRDSCVDKSRCAKYGYFQECTDCCKKYGHNGGTCMFFKCKCA
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Sequence Length
42
Mass (Da)
4802
Sequence Removed Signal Peptide
DRDSCVDKSRCAKYGYFQECTDCCKKYGHNGGTCMFFKCKCA
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Disulfide Bond
5-23;11-34;20-39;24-41
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides margaritatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv11 IC50
3.4 nM
 . . [1]
 Target Info    Kv11 IC50
3.4 nM
 .
Blocker
 [1]
References
Ref 1 Colombian Scorpion Centruroides margaritatus: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel. Toxins (Basel). 2021 Jun 8;13(6):407. doi: 10.3390/toxins13060407.
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