Peptide Information

General Information of This Peptide
Peptide ID
BTDP008593
Peptide Name
Kunitz-type serine protease inhibitor PPTI
Symonym
Pseudocerastes persicus trypsin inhibitor
Species
Pseudocerastes persicus (Persian horned viper) (False horned viper)
Uniprot Name
VKT_PSEPC
Alphafold ID
C0HLB2
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 6A5I
Sequence
EDRPKFCYLPDDPGVCKAHIPRFYYNPASNKCKEFIYGGCGGNANNFETRAECRHTCVAS
RKGGPRRP
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Sequence Length
68
Mass (Da)
7668
Sequence Removed Signal Peptide
EDRPKFCYLPDDPGVCKAHIPRFYYNPASNKCKEFIYGGCGGNANNFETRAECRHTCVAS
RKGGPRRP
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Disulfide Bond
7-57;16-40;32-53
PDB ID
6A5I
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Viperidae
Genus: Pseudocerastes
Species: Pseudocerastes persicus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2]
 Target Info    trypsin Inhibition constant
0.2 μM
 .
Blocker
 [1], [2]
References
Ref 1 Characterization of a new member of kunitz-type protein family from the venom of Persian false-horned viper, Pseudocerastes persicus. Arch Biochem Biophys. 2019 Feb 15;662:1-6. doi: 10.1016/j.abb.2018.11.017. Epub 2018 Nov 16.
Ref 2 Structural characterization of PPTI, a kunitz-type protein from the venom of Pseudocerastes persicus. PLoS One. 2019 Apr 11;14(4):e0214657. doi: 10.1371/journal.pone.0214657. eCollection 2019.
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