Peptide Information

General Information of This Peptide
Peptide ID
BTDP008569
Peptide Name
Peptide 2
Symonym
Peptide II
Species
Hottentotta tamulus sindicus (Scorpion) (Buthus sindicus)
Uniprot Name
KAX9J_HOTTS
Alphafold ID
P15230
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P15230
Sequence
VGCEEDPMHCKGKQAKPTCCNGVCNCNV
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Sequence Length
28
Mass (Da)
2968
Sequence Removed Signal Peptide
VGCEEDPMHCKGKQAKPTCCNGVCNCNV
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus tamulus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1]
 Target Info    Kv1.5 Inhibition rate .
10 nM
Blocker
 [2]
References
Ref 1 Characterization of two different peptides from the venom of the scorpion Buthus sindicus. FEBS Lett. 1989 Nov 6;257(2):260-2. doi: 10.1016/0014-5793(89)81548-0.
Ref 2 Vm24, a natural immunosuppressive peptide, potently and selectively blocks Kv1.3 potassium channels of human T cells. Mol Pharmacol. 2012 Sep;82(3):372-82. doi: 10.1124/mol.112.078006. Epub 2012 May 23.
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