Peptide Information

General Information of This Peptide
Peptide ID
BTDP008566
Peptide Name
U-actitoxin-Bcg2a
Symonym
AnmTX BC 9a-3; Bcg III 21.75
Species
Bunodosoma cangicum (Sea anemone)
Uniprot Name
TX9A7_BUNCN
Alphafold ID
P86465
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P86465
Sequence
NIVDVPCRDDYYRDSSGNGVYDQLGGCGAA
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Sequence Length
30
Mass (Da)
3180
Sequence Removed Signal Peptide
NIVDVPCRDDYYRDSSGNGVYDQLGGCGAA
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Disulfide Bond
727
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Kingdom: Metazoa
Phylum: Cnidaria
Class: Anthozoa
Order: Actiniaria
Family: Actiniidae
Genus: Bunodosoma
Species: Bunodosoma cangicum
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . . . [1], [2], [3]
References
Ref 1 Proteomics of the neurotoxic fraction from the sea anemone Bunodosoma cangicum venom: Novel peptides belonging to new classes of toxins. Comp Biochem Physiol Part D Genomics Proteomics. 2008 Sep;3(3):219-25. doi: 10.1016/j.cbd.2008.04.002. Epub 2008 Apr 26.
Ref 2 Development of a rational nomenclature for naming peptide and protein toxins from sea anemones. Toxicon. 2012 Sep 15;60(4):539-50. doi: 10.1016/j.toxicon.2012.05.020. Epub 2012 Jun 5.
Ref 3 Sea anemone peptide with uncommon -hairpin structure inhibits acid-sensing ion channel 3 (ASIC3) and reveals analgesic activity. J Biol Chem. 2013 Aug 9;288(32):23116-27. doi: 10.1074/jbc.M113.485516. Epub 2013 Jun 25.
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