Peptide Information

General Information of This Peptide
Peptide ID
BTDP008562
Peptide Name
Toxin KTx8
Symonym
LmKTx8
Species
Lychas mucronatus (Chinese swimming scorpion)
Uniprot Name
KA11L_LYCMC
Alphafold ID
A9QLM3
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: A9QLM3
Sequence
MNKVCFVVVLVLFVALAAYVSPIEGVPTGGCPLSDSLCAKYCKSHKFGKTGRCTGPNKMK
CKCLV
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Sequence Length
65
Mass (Da)
6912
Signal Sequence
MNKVCFVVVLVLFVALAAYVSPIEG
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Sequence Removed Signal Peptide
VPTGGCPLSDSLCAKYCKSHKFGKTGRCTGPNKMKCKCLV
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Disulfide Bond
31-53;38-61;42-63
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Lychas
Species: Lychas mucronatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa1.1 Inhibition rate .
100 nM
Blocker
 [1]
 Target Info    Kv1.3 IC50
26.4 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
26.4 nM
 .
Blocker
 [1]
References
Ref 1 Molecular cloning and electrophysiological studies on the first K(+) channel toxin (LmKTx8) derived from scorpion Lychas mucronatus. Peptides. 2007 Dec;28(12):2306-12. doi: 10.1016/j.peptides.2007.10.009. Epub 2007 Oct 22.
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