Peptide Information

General Information of This Peptide
Peptide ID
BTDP008549
Peptide Name
Potassium channel toxin TstKMK
Symonym
Toxin 5536; beta-Ktx
Species
Tityus stigmurus (Brazilian scorpion)
Uniprot Name
KBX2_TITST
Alphafold ID
P0C8W4
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C8W4
Sequence
MVATNRCCVFALLFALLLVHSLTEAGKGKEILGKIKEKIIEAKDKMKAGWERLTSQSEYA
CPAIDKFCEDHCAAKKAVGKCDDFKCKCIKL
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Sequence Length
91
Mass (Da)
10097
Signal Sequence
MVATNRCCVFALLFALLLVHSLTEA
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Sequence Removed Signal Peptide
GKGKEILGKIKEKIIEAKDKMKAGWERLTSQSEYACPAIDKFCEDHCAAKKAVGKCDDFK
CKCIKL
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Disulfide Bond
61-81;68-86;72-88
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus stigmurus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2]
References
Ref 1 Molecular approaches for structural characterization of a new potassium channel blocker from Tityus stigmurus venom: cDNA cloning, homology modeling, dynamic simulations and docking. Biochem Biophys Res Commun. 2013 Jan 4;430(1):113-8. doi: 10.1016/j.bbrc.2012.11.044. Epub 2012 Nov 27.
Ref 2 Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Jul-Aug;146(1-2):147-157. doi: 10.1016/j.cbpc.2006.12.004. Epub 2006 Dec 16.
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