Peptide Information

General Information of This Peptide
Peptide ID
BTDP008546
Peptide Name
Potassium channel toxin Tdi-beta-KTx
Symonym
TdibetaKTx
Species
Tityus discrepans (Venezuelan scorpion)
Uniprot Name
KBX1_TITDI
Alphafold ID
Q0GY44
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q0GY44
Sequence
MERKLALLLLLGMITLASSGLREKHVQKLVTLIPNDTLRSIMKTIVHKLAKTQFGCPAYE
GYCMNHCQDIERHDGSCHGFKCKCEKS
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Sequence Length
87
Mass (Da)
9833
Signal Sequence
MERKLALLLLLGMITLASS
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Sequence Removed Signal Peptide
GLREKHVQKLVTLIPNDTLRSIMKTIVHKLAKTQFGCPAYEGYCMNHCQDIERHDGSCHG
FKCKCEKS
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Disulfide Bond
56-77;63-82;67-84
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus discrepans
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2], [3]
References
Ref 1 Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components. Peptides. 2007 Jan;28(1):31-7. doi: 10.1016/j.peptides.2006.06.012. Epub 2006 Dec 1.
Ref 2 Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans. Biochimie. 2009 Aug;91(8):1010-9. doi: 10.1016/j.biochi.2009.05.005. Epub 2009 May 24.
Ref 3 Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins. Proteomics. 2006 Jun;6(12):3718-27. doi: 10.1002/pmic.200500525.
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