General Information of This Peptide
Peptide ID
BTDP008538
Peptide Name
Potassium channel toxin Hge-beta-KTx
Symonym
HgebetaKTx
Species
Hoffmannihadrurus gertschi (Scorpion) (Hadrurus gertschi)
Uniprot Name
KBX2_HOFGE
Alphafold ID
Q0GY41
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q0GY41
Sequence
MAKSFFAAFLIIMLISSLVDGKSTVGQKLKKKLNQAVDKVKEVLNKSEYMCPVVSSFCKQ
HCARLGKSGQCDLLECICS
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Sequence Length
79
Mass (Da)
8689
Signal Sequence
MAKSFFAAFLIIMLISSLVDG
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Sequence Removed Signal Peptide
KSTVGQKLKKKLNQAVDKVKEVLNKSEYMCPVVSSFCKQHCARLGKSGQCDLLECICS
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Disulfide Bond
51-71;58-76;62-78
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Caraboctonidae
Genus: Hadrurus
Species: Hadrurus gertschi
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
[1], [2], [3]
References
Ref 1 Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones). BMC Genomics. 2007 May 16;8:119. doi: 10.1186/1471-2164-8-119.
Ref 2 Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components. Peptides. 2007 Jan;28(1):31-7. doi: 10.1016/j.peptides.2006.06.012. Epub 2006 Dec 1.
Ref 3 Cytolytic and K+ channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms. Cell Mol Life Sci. 2008 Jan;65(1):187-200. doi: 10.1007/s00018-007-7370-x.
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