Peptide Information

General Information of This Peptide
Peptide ID
BTDP008533
Peptide Name
Potassium channel toxin BmTXK-beta
Symonym
BmKLK; Potassium channel toxin beta-KTx 3; Toxin BmTX K-beta
Species
Mesobuthus martensii (Manchurian scorpion) (Buthus martensii)
Uniprot Name
KBX2_MESMA
Alphafold ID
Q9NJC6
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q9NJC6
Sequence
MMKQQFFLFLAVIVMISSVIEAGRGKEIMKNIKEKLTEVKDKMKHSWNKLTSMSEYACPV
IEKWCEDHCAAKKAIGKCEDTECKCLKLRK
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Sequence Length
90
Mass (Da)
10431
Signal Sequence
MMKQQFFLFLAVIVMISSVIEA
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Sequence Removed Signal Peptide
GRGKEIMKNIKEKLTEVKDKMKHSWNKLTSMSEYACPVIEKWCEDHCAAKKAIGKCEDTE
CKCLKLRK
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Disulfide Bond
58-78;65-83;69-85
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus martensii
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2], [3], [4]
References
Ref 1 Molecular cloning and sequencing of two 'short chain' and two 'long chain' K(+) channel-blocking peptides from the Chinese scorpion Buthus martensii Karsch. FEBS Lett. 1999 Sep 3;457(3):509-14. doi: 10.1016/s0014-5793(99)01101-1.
Ref 2 A naturally occurring non-coding fusion transcript derived from scorpion venom gland: implication for the regulation of scorpion toxin gene expression. FEBS Lett. 2001 Nov 16;508(2):241-4. doi: 10.1016/s0014-5793(01)03067-8.
Ref 3 Evidence that BmTXK beta-BmKCT cDNA from Chinese scorpion Buthus martensii Karsch is an artifact generated in the reverse transcription process. FEBS Lett. 2002 Jun 5;520(1-3):183-4; author reply 185. doi: 10.1016/s0014-5793(02)02812-0.
Ref 4 Expression, purification and functional characterization of a recombinant scorpion venom peptide BmTXKbeta. Peptides. 2003 Feb;24(2):187-92. doi: 10.1016/s0196-9781(03)00025-1.
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