Peptide Information

General Information of This Peptide
Peptide ID
BTDP008470
Peptide Name
Potassium channel toxin alpha-KTx 17.1
Symonym
BmKK4; Toxin Kk4; Toxin TXKs4
Species
Mesobuthus martensii (Manchurian scorpion) (Buthus martensii)
Uniprot Name
KA171_MESMA
Alphafold ID
Q95NJ8
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 1S8K
Sequence
MKFIIVLILISVLIATIVPVNEAQTQCQSVRDCQQYCLTPDRCSYGTCYCKTTGK
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Sequence Length
55
Mass (Da)
6161
Signal Sequence
MKFIIVLILISVLIATIVPVNEA
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Sequence Removed Signal Peptide
QTQCQSVRDCQQYCLTPDRCSYGTCYCKTTGK
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Disulfide Bond
27-43;33-48;37-50
PDB ID
1S8K
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Mesobuthus
Species: Mesobuthus martensii
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2], [3]
References
Ref 1 Molecular cloning and characterization of four scorpion K(+)-toxin-like peptides: a new subfamily of venom peptides (alpha-KTx14) and genomic analysis of a member. Biochimie. 2001 Sep;83(9):883-9. doi: 10.1016/s0300-9084(01)01326-8.
Ref 2 BmKK4, a novel toxin from the venom of Asian scorpion Buthus martensi Karsch, inhibits potassium currents in rat hippocampal neurons in vitro. Toxicon. 2003 Aug;42(2):199-205. doi: 10.1016/s0041-0101(03)00136-3.
Ref 3 Solution structure of BmKK4, the first member of subfamily alpha-KTx 17 of scorpion toxins. Biochemistry. 2004 Oct 5;43(39):12469-76. doi: 10.1021/bi0490643.
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