Peptide Information

General Information of This Peptide
Peptide ID
BTDP008462
Peptide Name
Potassium channel toxin alpha-KTx 13.3
Symonym
Toxin Tpa1
Species
Tityus pachyurus (Colombian scorpion)
Uniprot Name
KA133_TITPA
Alphafold ID
P84630
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P84630
Sequence
ACGSCRKKCKGPGKCINGRCKCY
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Sequence Length
23
Mass (Da)
2464
Sequence Removed Signal Peptide
ACGSCRKKCKGPGKCINGRCKCY
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Disulfide Bond
2-15;5-20;9-22
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Tityus
Species: Tityus pachyurus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Shaker Dissociation constant
200 nM
 .
Blocker
 [1]
 Target Info    Shaker B potassium channel Dissociation constant
200 nM
 .
Blocker
 [2]
References
Ref 1 Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities. Biochim Biophys Acta. 2002 Dec 16;1601(2):123-31. doi: 10.1016/s1570-9639(02)00458-2.
Ref 2 Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus. Biochim Biophys Acta. 2006 Jan;1764(1):76-84. doi: 10.1016/j.bbapap.2005.08.010. Epub 2005 Aug 26.
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