Peptide Information

General Information of This Peptide
Peptide ID
BTDP008456
Peptide Name
Potassium channel toxin alpha-KTX 12 Sp2
Symonym
KTX-Sp2
Species
Scorpiops pococki (Scorpion)
Uniprot Name
KA12O_SCOPC
Alphafold ID
P0DQN5
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P0DQN5
Sequence
MRLAIILLLMTTIVLTIGSPLHGAKCSSSNQCTRPCRYGGGTHGKCMNGRCRCYG
   Click to Show/Hide
Sequence Length
55
Mass (Da)
5902
Signal Sequence
MRLAIILLLMTTIVLTIG
   Click to Show/Hide
Sequence Removed Signal Peptide
SPLHGAKCSSSNQCTRPCRYGGGTHGKCMNGRCRCYG
   Click to Show/Hide
Disulfide Bond
26-46;32-51;36-53
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Euscorpiidae
Genus: Scorpiops
Species: Scorpiops pococki
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 IC50
0.3 - 30 nM
 .
Blocker
 [1]
 Target Info    Kv1.3 IC50
14.7 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 IC50
56.9 nM
 .
Blocker
 [1]
 Target Info    Kv1.2 IC50
57 nM
 .
Blocker
 [1]
 Target Info    Kv1.1 IC50
485 nM
 .
Blocker
 [1]
 Target Info    Kv1.1 IC50
485 nM
 .
Blocker
 [1]
References
Ref 1 Immunosuppressive effects of a novel potassium channel toxin Ktx-Sp2 from Scorpiops Pocoki. Cell Biosci. 2019 Dec 16;9:99. doi: 10.1186/s13578-019-0364-1. eCollection 2019.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.