Peptide Information

General Information of This Peptide
Peptide ID
BTDP008445
Peptide Name
Potassium channel toxin alpha-KTx 1.11
Symonym
Slotoxin
Species
Centruroides noxius (Mexican scorpion)
Uniprot Name
KAX1B_CENNO
Alphafold ID
P0C182
3D Structure
Download
2D Sequence
3D Structure
Source
Alphafold db: P0C182
Sequence
TFIDVDCTVSKECWAPCKAAFGVDRGKCMGKKCKCYV
   Click to Show/Hide
Sequence Length
37
Mass (Da)
4092
Sequence Removed Signal Peptide
TFIDVDCTVSKECWAPCKAAFGVDRGKCMGKKCKCYV
   Click to Show/Hide
Disulfide Bond
7-28;13-33;17-35
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
Species: Centruroides noxius
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa1.1 Dissociation constant
1.5 nM
 .
Blocker
 [1]
 Target Info    Kv11 Inhibition rate .
300 nM
Blocker
 [1]
 Target Info    Kir2.1 Inhibition rate .
300 nM
Blocker
 [1]
 Target Info    Kv1.1 Inhibition rate .
300 nM
Blocker
 [1]
 Target Info    Shaker-IR Inhibition rate .
350 nM
Blocker
 [1]
 Target Info    KCa2.1 Inhibition rate .
500 nM
Blocker
 [1]
 Target Info    KCa2.2 Inhibition rate .
500 nM
Blocker
 [1]
 Target Info    KCa2.3 Inhibition rate .
500 nM
Blocker
 [1]
References
Ref 1 Slotoxin, alphaKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between alpha and alpha+beta (beta1 or beta4) complexes. FEBS Lett. 2001 Sep 21;505(3):369-73. doi: 10.1016/s0014-5793(01)02791-0.
Data Quality & Feedback

Help us maintain data quality by reporting any errors or inaccuracies you may find.

samedaypayday.com visits since 2024

If you find any error in data or bug in web service, please kindly report it to biodb_contact@163.com et al.