Peptide Information

General Information of This Peptide
Peptide ID
BTDP008443
Peptide Name
Potassium channel toxin AaTXK-beta
Symonym
Potassium channel toxin AaTXK-beta(1-64); Potassium channel toxin beta-KTx 2
Species
Androctonus australis (Sahara scorpion)
Uniprot Name
KBX1_ANDAU
Alphafold ID
P69939
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P69939
Sequence
MQRNLVVLLFLGMVALSSCGLREKHVQKLVKYAVPVGTLRTILQTVVHKVGKTQFGCPAY
QGYCDDHCQDIKKEEGFCHGFKCKCGIPMGF
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Sequence Length
91
Mass (Da)
10148
Signal Sequence
MQRNLVVLLFLGMVALSSC
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Sequence Removed Signal Peptide
GLREKHVQKLVKYAVPVGTLRTILQTVVHKVGKTQFGCPAYQGYCDDHCQDIKKEEGFCH
GFKCKCGIPMGF
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Disulfide Bond
57-78;64-83;68-85
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Androctonus
Species: Androctonus australis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . .
Blocker
 [1], [2]
References
Ref 1 Evidence for a new class of scorpion toxins active against K+ channels. FEBS Lett. 1998 Jul 24;431(3):375-80. doi: 10.1016/s0014-5793(98)00780-7.
Ref 2 Subtype-selective activation of K(v)7 channels by AaTXK????, a novel toxin variant from the Androctonus australis scorpion venom. Mol Pharmacol. 2013 Nov;84(5):763-73. doi: 10.1124/mol.113.088971. Epub 2013 Sep 9.
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