Peptide Information

General Information of This Peptide
Peptide ID
BTDP008432
Peptide Name
Myotoxin
Symonym
CAM-toxin
Species
Crotalus adamanteus (Eastern diamondback rattlesnake)
Uniprot Name
MYX_CROAD
Alphafold ID
P24330
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P24330
Sequence
MKILYLLFAFLFLAFLSEPGNAYKRCHKKGGHCFPKTVICLPPSSDFGKMDCRWRWKCCK
KGSVNNAISI
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Sequence Length
70
Mass (Da)
8017
Signal Sequence
MKILYLLFAFLFLAFLSEPGNA
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Sequence Removed Signal Peptide
YKRCHKKGGHCFPKTVICLPPSSDFGKMDCRWRWKCCKKGSVNNAISI
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Disulfide Bond
26-58;33-52;40-59
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Viperidae
Genus: Crotalus
Species: Crotalus adamanteus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . . . [1], [2], [3], [4]
References
Ref 1 The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus). BMC Genomics. 2012 Jul 16;13:312. doi: 10.1186/1471-2164-13-312.
Ref 2 A high-throughput venom-gland transcriptome for the Eastern Diamondback Rattlesnake (Crotalus adamanteus) and evidence for pervasive positive selection across toxin classes. Toxicon. 2011 Apr;57(5):657-71. doi: 10.1016/j.toxicon.2011.01.008. Epub 2011 Jan 19.
Ref 3 Amino acid sequence of a myotoxin from venom of the eastern diamondback rattlesnake (Crotalus adamanteus). Toxicon. 1991;29(4-5):461-8. doi: 10.1016/0041-0101(91)90020-r.
Ref 4 Linking the transcriptome and proteome to characterize the venom of the eastern diamondback rattlesnake (Crotalus adamanteus). J Proteomics. 2014 Jan 16;96:145-58. doi: 10.1016/j.jprot.2013.11.001. Epub 2013 Nov 12.
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