Peptide Information

General Information of This Peptide
Peptide ID
BTDP008385
Peptide Name
Kappa-lycotoxin-Os1a
Symonym
Toxin Osu1
Species
Oculicosa supermirabilis (Central Asian wolf-spider)
Uniprot Name
TX1_OCUSU
Alphafold ID
C0HLR8
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: C0HLR8
Sequence
RLALPPGAVCNGHKSDCQCFGAKYKCSCPFFWRFRKSAECHCKKGWAWTAIKKRSCHNRY
QWSD
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Sequence Length
64
Mass (Da)
7486
Sequence Removed Signal Peptide
RLALPPGAVCNGHKSDCQCFGAKYKCSCPFFWRFRKSAECHCKKGWAWTAIKKRSCHNRY
QWSD
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Disulfide Bond
10-26;17-56;19-42;28-40
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Araneae
Family: Lycosidae
Genus: Oculicosa
Species: Oculicosa supermirabilis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.5 Inhibition rate
10 %
3 μM
Blocker
 [1]
References
Ref 1 A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5. Front Pharmacol. 2021 Jan 13;11:563858. doi: 10.3389/fphar.2020.563858. eCollection 2020.
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