Peptide Information

General Information of This Peptide
Peptide ID
BTDP008378
Peptide Name
Kappa-conotoxin BtX
Symonym
BeTx
Species
Conus betulinus (Beech cone)
Uniprot Name
I2B_CONBE
Alphafold ID
Q9U3Z3
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q9U3Z3
Sequence
MMFRVTSVGCLLLVIVFLNLVVPTSACRAEGTYCENDSQCCLNECCWGGCGHPCRHPGKR
SKLQEFFRQR
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Sequence Length
70
Mass (Da)
7900
Signal Sequence
MMFRVTSVGCLLLVIVFLNLVVPTSA
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Sequence Removed Signal Peptide
CRAEGTYCENDSQCCLNECCWGGCGHPCRHPGKRSKLQEFFRQR
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Disulfide Bond
27-41;34-46;40-50;45-54
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus betulinus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    KCa1.1 Effective concentration 50
0.7 nM
 .
Activator
 [1]
References
Ref 1 A novel conotoxin from Conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator. J Biol Chem. 2003 Apr 11;278(15):12624-33. doi: 10.1074/jbc.M210200200. Epub 2003 Jan 23.
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