Peptide Information

General Information of This Peptide
Peptide ID
BTDP008366
Peptide Name
Cysteine-rich venom protein kaouthin-1
Symonym
Cysteine-rich venom protein 25
Species
Naja kaouthia (Monocled cobra) (Naja siamensis)
Uniprot Name
CRVP1_NAJKA
Alphafold ID
P84805
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P84805
Sequence
MIAFSLLCLAAVLRQSFGNVDFNSESTRRKKKQKEIVDLHNSLRRRVSPTASNMLKMEWY
PEAASNAERWANTCSLNHSPDNLRVLEGIQCGESIYMSSNARTWTEIIHLWHDEYKNFVY
GVGANPPGSVTGHYTQIVWYQTYRAGCAVSYCPSSAWSYFYVCQYCPSGNFQGKTATPYK
LGPPCGDCPSACDNGLCTNPCTIYNKLTNCDSLLKQGSCQDDWIKSNCPASCFCRNKII
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Sequence Length
239
Mass (Da)
26846
Signal Sequence
MIAFSLLCLAAVLRQSFG
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Sequence Removed Signal Peptide
NVDFNSESTRRKKKQKEIVDLHNSLRRRVSPTASNMLKMEWYPEAASNAERWANTCSLNH
SPDNLRVLEGIQCGESIYMSSNARTWTEIIHLWHDEYKNFVYGVGANPPGSVTGHYTQIV
WYQTYRAGCAVSYCPSSAWSYFYVCQYCPSGNFQGKTATPYKLGPPCGDCPSACDNGLCT
NPCTIYNKLTNCDSLLKQGSCQDDWIKSNCPASCFCRNKII
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Disulfide Bond
74-152;91-166;147-163;185-192;188-197;201-234;210-228;219-232
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Elapidae
Genus: Naja
Species: Naja kaouthia
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    potassium channels . . . . [1], [2]
References
Ref 1 Structural divergence of cysteine-rich secretory proteins in snake venoms. J Biochem. 2009 Mar;145(3):365-75. doi: 10.1093/jb/mvn174. Epub 2008 Dec 23.
Ref 2 Cobra venom contains a pool of cysteine-rich secretory proteins. Biochem Biophys Res Commun. 2005 Mar 4;328(1):177-82. doi: 10.1016/j.bbrc.2004.12.154.
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