Peptide Information

General Information of This Peptide
Peptide ID
BTDP008359
Peptide Name
Conotoxin SIVA
Symonym
Conotoxin S4.1; Conotoxin s4a; Kappa-conotoxin SIVA; KappaA-conotoxin; Spastic peptide
Species
Conus striatus (Striated cone)
Uniprot Name
CA4A_CONST
Alphafold ID
P0C828
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P0C828
Sequence
MGMRMMFTVFLLVVLATTVVSTPSDRASDGRNAAVHERQKSLVPSVITTCCGYDPGTMCP
PCRCTNSCG
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Sequence Length
69
Mass (Da)
7373
Signal Sequence
MGMRMMFTVFLLVVLATTVVS
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Sequence Removed Signal Peptide
TPSDRASDGRNAAVHERQKSLVPSVITTCCGYDPGTMCPPCRCTNSCG
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        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conus
Species: Conus striatus
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Shaker . . . . [1- 5]
References
Ref 1 cDNA cloning of two A-superfamily conotoxins from Conus striatus. Toxicon. 2003 Nov;42(6):613-9. doi: 10.1016/j.toxicon.2003.08.005.
Ref 2 The A-superfamily of conotoxins: structural and functional divergence. J Biol Chem. 2004 Apr 23;279(17):17596-606. doi: 10.1074/jbc.M309654200. Epub 2003 Dec 30.
Ref 3 Two toxins from Conus striatus that individually induce tetanic paralysis. Biochemistry. 2006 Nov 28;45(47):14212-22. doi: 10.1021/bi061485s.
Ref 4 Analysis of expressed sequence tags from the venom ducts of Conus striatus: focusing on the expression profile of conotoxins. Biochimie. 2006 Feb;88(2):131-40. doi: 10.1016/j.biochi.2005.08.001. Epub 2005 Sep 8.
Ref 5 An O-glycosylated neuroexcitatory conus peptide. Biochemistry. 1998 Nov 17;37(46):16019-25. doi: 10.1021/bi981690a.
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