Peptide Information

General Information of This Peptide
Peptide ID
BTDP008334
Peptide Name
Alpha-conotoxin Lo1a
Species
Conasprella longurionis (Cone snail) (Conus longurionis)
Uniprot Name
CA1A_CONLG
Alphafold ID
X1WB75
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 2MD6
Sequence
EGCCSNPACRTNHPEVCD
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Sequence Length
18
Mass (Da)
1935
Sequence Removed Signal Peptide
EGCCSNPACRTNHPEVCD
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Disulfide Bond
3-9;4-17
PDB ID
2MD6
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Kingdom: Metazoa
Phylum: Mollusca
Class: Gastropoda
Order: Neogastropoda
Family: Conidae
Genus: Conasprella
Species: Conasprella longurionis
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    nAChR alpha-7 IC50
3.24 μM
 . . [1]
References
Ref 1 Structure-function elucidation of a new -conotoxin, Lo1a, from Conus longurionis. J Biol Chem. 2014 Apr 4;289(14):9573-83. doi: 10.1074/jbc.M114.556175. Epub 2014 Feb 24.
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