Peptide Information

General Information of This Peptide
Peptide ID
BTDP007300
Peptide Name
Amblin
Symonym
Thrombin inhibitor
Species
Amblyomma hebraeum (South African bont tick)
Uniprot Name
KUNI_AMBHE
Alphafold ID
Q5VJG2
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: Q5VJG2
Sequence
MGFLVASAVLVCVTSQRVPGYCKKKPAVGPCKALIEKWYFDYSTQSCKTFYYGGCGGNGN
KFSSRKKCREACLPKRPSVPVCKQMPDPGFCRAYMPHWFFNSKSGYCEGFVYGGCQGNDN
RFKSCWQCMKKCRTAREANRLCWKLTKEFNKKFLRNVPTAKPLPPK
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Sequence Length
166
Mass (Da)
18882
Signal Sequence
MGFLVASAVLVCVTS
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Sequence Removed Signal Peptide
QRVPGYCKKKPAVGPCKALIEKWYFDYSTQSCKTFYYGGCGGNGNKFSSRKKCREACLPK
RPSVPVCKQMPDPGFCRAYMPHWFFNSKSGYCEGFVYGGCQGNDNRFKSCWQCMKKCRTA
REANRLCWKLTKEFNKKFLRNVPTAKPLPPK
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Disulfide Bond
22-72;31-55;47-68;82-132;91-115;107-128
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Ixodida
Family: Ixodidae
Genus: Amblyomma
Species: Amblyomma hebraeum
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    thrombin Inhibition constant
20 nM
 . . [1]
References
Ref 1 A thrombin inhibitor from the ixodid tick, Amblyomma hebraeum. Gene. 2004 Nov 24;342(2):243-9. doi: 10.1016/j.gene.2004.07.012.
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