Peptide Information

General Information of This Peptide
Peptide ID
BTDP006894
Peptide Name
Zinc metalloproteinase barnettlysin-1
Symonym
Barnettlysin-I; Snake venom metalloproteinase
Species
Bothrops barnetti (Barnett's lancehead) (Trimeresurus barnetti)
Uniprot Name
VM1B1_BOTBA
3D Structure
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2D Sequence
3D Structure
Source
Predict by Alphafold2
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Alphafold Parameters: msa_mode: mmseqs2_uniref_env model_type: auto num_recycles: auto
Sequence
TPEQQRYVELFIVVDHGMFMKXXXXXXXXXXXIHQMVNIMKEAYRYLYIDILLTGVEIWS
NKDLINVQPAAPQTLDSFGEWRXXXXXXXKSHDNAQLLTSTDFDGPTIGLAYVGSMCDPK
RSTAVIQDHSEIDLLVAVTMDHELGHNLGIRHDTGSCSCGGYPCVMSPVISHDISKYFSD
CSYIQCWDFIMKENPQCILNKR
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Sequence Length
202
Mass (Da)
22927
Sequence Removed Signal Peptide
TPEQQRYVELFIVVDHGMFMKXXXXXXXXXXXIHQMVNIMKEAYRYLYIDILLTGVEIWS
NKDLINVQPAAPQTLDSFGEWRXXXXXXXKSHDNAQLLTSTDFDGPTIGLAYVGSMCDPK
RSTAVIQDHSEIDLLVAVTMDHELGHNLGIRHDTGSCSCGGYPCVMSPVISHDISKYFSD
CSYIQCWDFIMKENPQCILNKR
   Click to Show/Hide
Disulfide Bond
117-197;157-181;159-164
        Click to Show/Hide the Complete Species Lineage
Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Viperidae
Genus: Bothrops
Species: Bothrops barnetti
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    von Willebrand factor (VWF) IC50
1.4 μM
 . . [1]
 Target Info    type I collagen IC50
3.2 μM
 . . [1]
References
Ref 1 A novel fibrinolytic metalloproteinase, barnettlysin-I from Bothrops barnetti (Barnetts pitviper) snake venom with anti-platelet properties. Biochim Biophys Acta. 2016 Mar;1860(3):542-56. doi: 10.1016/j.bbagen.2015.12.021. Epub 2015 Dec 23.
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