Peptide Information

General Information of This Peptide
Peptide ID
BTDP006032
Peptide Name
Ornithodorin
Symonym
Thrombin inhibitor
Species
Ornithodoros moubata (Soft tick) (Argasid tick)
Uniprot Name
KUNI_ORNMO
Alphafold ID
P56409
3D Structure
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2D Sequence
3D Structure
Source
RSCB PDB: 1TOC
Sequence
LNVLCNNPHTADCNNDAQVDRYFREGTTCLMSPACTSEGYASQHECQQACFVGGEDHSSE
MHSSCLGDPPTSCAEGTDITYYDSDSKTCKVLAASCPSGENTFESEVECQVACGAPIEG
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Sequence Length
119
Mass (Da)
12632
Sequence Removed Signal Peptide
LNVLCNNPHTADCNNDAQVDRYFREGTTCLMSPACTSEGYASQHECQQACFVGGEDHSSE
MHSSCLGDPPTSCAEGTDITYYDSDSKTCKVLAASCPSGENTFESEVECQVACGAPIEG
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Disulfide Bond
5-50;13-35;29-46;65-113;73-96;89-109
PDB ID
1TOC
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Kingdom: Metazoa
Phylum: Arthropoda
Class: Arachnida
Order: Ixodida
Family: Argasidae
Genus: Ornithodoros
Species: Ornithodoros moubata
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    thrombin Inhibition constant
10 pM
 . . [1]
References
Ref 1 The ornithodorin-thrombin crystal structure, a key to the TAP enigma?. EMBO J. 1996 Nov 15;15(22):6011-7.
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