Peptide Information

General Information of This Peptide
Peptide ID
BTDP005863
Peptide Name
Kunitz-type serine protease inhibitor
Symonym
Venom trypsin inhibitor
Species
Eristicophis macmahoni (Leaf-nosed viper)
Uniprot Name
VKT_ERIMA
Alphafold ID
P24541
3D Structure
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2D Sequence
3D Structure
Source
Alphafold db: P24541
Sequence
FCYLPDDPGVCKAHIPRFYYNPASNKCKNFIYGGCGGNANNFETRAECRHTCVASGKGGP
RP
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Sequence Length
62
Mass (Da)
6772
Sequence Removed Signal Peptide
FCYLPDDPGVCKAHIPRFYYNPASNKCKNFIYGGCGGNANNFETRAECRHTCVASGKGGP
RP
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Disulfide Bond
2-52;11-35;27-48
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Kingdom: Metazoa
Phylum: Chordata
Class: Lepidosauria
Order: Squamata
Family: Viperidae
Genus: Eristicophis
Species: Eristicophis macmahoni
Full List of Activity Data of This Peptide Toxin
                        Target Name Activity Data Type Activity Data Concentration Note Reference
 Target Info    Kv1.3 Inhibition rate
3.7 %
60 nM
 . [1], [2]
References
Ref 1 Purification and characterization of a Kunitz-type trypsin inhibitor from Leaf-nosed viper venom. FEBS Lett. 1991 Dec 2;294(1-2):141-3. doi: 10.1016/0014-5793(91)81361-b.
Ref 2 Identification of novel Kv1.3 targeting venom peptides by a single round of autocrine-based selection. Biochem Biophys Res Commun. 2019 Feb 19;509(4):954-959. doi: 10.1016/j.bbrc.2019.01.014. Epub 2019 Jan 14.
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